Biotech x FoodTech: When Two Revolutions Collide

Published on September 30, 2025

We recently held a webinar in the context of Biotech4Food, the European initiative to accelerate the adoption of biotech technologies in the agrifood value chain. It was a great opportunity to think about the growing links between the Biotech and FoodTech ecosystems. While it’s easy to confine Biotech to the realm of pharma and MedTech, the technologies developed there, such as microbial fermentation and molecular farming, have now become key to the food industry. While this convergence is becoming increasingly apparent for startups and investors, it creates multiple uncertainties for incumbent businesses.

1 – What do we mean when we talk about the intersection of FoodTech and Biotech?

If we go back to the basics, biotech can be split into three spaces:

  • Red biotech: medical and healthcare applications
  • Green biotech: agriculture (bioinputs, livestock health, new crops)
  • White biotech: industrial processes and ingredients.

Another way to look at the intersection is to consider the different FoodTech spaces where biotechnologies are being used.

As shown in the above DigitalFoodLab’s trend curve, FoodTech and Biotech intersect in almost all the most forward-looking trends, notably in these three megatrends:

  • Resilient Farming: making farming more sustainable and resilient to climate shocks requires the development of bioinputs and biostimulants (often leveraging micro-organisms to substitute chemicals), feed additives and vaccines to reduce methane emissions from livestock, and genomic engineering for crops.
  • Sustainable ingredients: to develop alternatives to animal proteins and ingredients to alleviate shortages (coffee, cocoa…), biotechnologies such as precision fermentation (mostly named microbial fermentation in the pharma space) and molecular farming (or pharming) are used. Interestingly, when moving from the pharma space to food, the names have been changed, as if to try to make these technologies look more cutting edge than what they actually are.
  • Healthy ageing: this last megatrend, which notably seeks to develop a new range of food ingredients that can have a positive health impact (new sugars, GLP-1 companions…) is the most visible testimony of the growing convergence of the Biotech and FoodTech spaces.

2 – A long-lasting trend that won’t fade away

Not all FoodTech trends are born equal, as some wither away before being given the chance to be really experimented with. However, in our case, everything is pointing towards a greater “Biotechification” of FoodTech and indeed of agriculture and food in general.

Helped by growing support from public organisations and governments, biotechnologies are often seen as one of the key technologies of the future, a source of wealth, highly qualified employment through re-industrialisation, and competitiveness. This explains why most developed countries have recently announced plans to support the scaling up of the biotech industry, most of them explicitly including agriculture and food applications as a key component of their strategy. Just in the past 12 months, the EU announced a €350M, followed by some EU national plans, the UK, South Korea, China… while the US already has a multi-billion-dollar strategy established.

3 – Serious strategic implications for agrifood leaders

For most large agrifood companies whose value relies on marketing and process capabilities, this is a total change of paradigm. Waiting until startups and other innovators develop the technologies enough for them to be ready to pick up, as any other ingredient won’t cut it.

There are multiple paths that agrifood players can follow, among which the three most obvious:

  • Partnerships + supplier relationship: CPG companies can avoid entering this space and follow the usual pattern of leveraging new ingredients developed through biotechnologies in their products. However, this is a high-risk scenario: if the new ingredients (notably those with health and sustainability benefits) become recognised by the consumer, the value will follow, and these companies would see their margins shrink.
  • Interested buyer relationship: by building capital relationships with biotechnology players, industry leaders can spread their bets and better prepare for potential shifts in their value chain.
  • Integration: by directly owning (by internal development or more usually by acquisitions), industry leaders can better integrate the value created by biotechnologies. While the rewards are high, the bets are much more costly. This is, however, what many upstream players (agriculture inputs and ingredient suppliers) are currently doing.

Navigating this increasing complexity requires a clear vision of the different trends and an honest assessment of a company’s capabilities. It also opens many opportunities and markets (such as the ones we recently explored in this insight). But, in a word, if today an agrifood company has not yet developed its “biotech strategy”, that is something they should do very soon.

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Use case: project for a global F&B company looking to map its AgTech innovation ecosystem and the best startups to partner with

What we did:

  • Mapping of the AgTech ecosystem: startups, research regulators, and other leading companies.
  • Discussion to select areas to focus on.
  • Analysis of the information to reveal the trends and a model to analyse eventual partners.
  • A workshop to validate the opportunities based on our recommendations.
  • Scouting of relevant partners followed by introductions.

Results:

  • Mapping the different categories of innovations in AgTech that should be considered now to create long-term benefits for the business.
  • Identification of key partners (an incubator and a couple of startups).

Use case: project for a CPG company on the healthy ageing ecosystem

What we did:

  • Education of the board through a couple of workshops to define the perimeter
  • Identification of key opportunities and threats created by long-term evolutions (technologies, business models, behavioural changes).
  • Deep dives on each of the priority categories.
  • Co-construction of a vision on how the company should address these challenges.
  • Identification of partners (startups, incubators, funds) to move forward.

Results:

  • Creating a consensus on which categories to prioritise and how to address them.
  • Implementation of an open innovation strategy through the development of partnerships.

Use case: project for a global CPG company to develop a strategy on the healthy ageing ecosystem

What we do (ongoing mission on a subscription model):

  • Kick-off where we present an overview of the AgriFoodTech ecosystem to select with the client the categories to cover and for each, the level of information required.
  • Monthly newsletter: each month we send a newsletter with the articles that we have gathered ranked by relevance, their summaries, and a layer of analysis.
  • Database: we set up a personalised database that will be filled month after month with the information gathered on the companies identified for the watch.
  • Workshops: twice a year with the client’s innovation team and other “innovation curious” team members, we present an overview of the evolutions, key trends and a dashboard of the topics followed by the watch.

Results:

  • A clear, regular and evolutive tool to follow what is happening in terms of innovation on key topics.
  • A forum (through the workshops) to discuss innovation trends and new opportunities.

Use case: opportunity screening for an ingredient company

What we did:

  • Kick-off to define the perimeter of the ecosystem studied.
  • Mapping of the different trends shaping the innovation ecosystem of the client.
  • Analysis of the trends on DigitalFoodLab’s trend curve and other relevant frameworks.
  • Workshop to discuss DigitalFoodLab’s recommendations on key trends to prioritise

Results:

  • Shared view of the innovation ecosystem for the client with a view of the trends to prioritize.
  • Clear document (personalised trend curve) that can be easily shared internaly to explain the company’s innovation choices and which can be then updated each year.

Use case: scouting for an agriculture coop

What we did:

  • Kick-off to define the perimeter of the client, the goals of the scouting (partnerships) and the criteria on which startups should be evaluated.
  • Set-up scouting: we selected the first batch of 20+ key startups following the criteria of the client.
  • On-going scouting: then we set up a quarterly scouting of about ten startups.
  • For each scouted startup, we created an ID card with key information such as the business and technological maturity, funding, and corporate partnerships. We also added an explanation of why we selected this startup.

Results:

  • An ongoing and evolutive scouting are matching the client's criteria and its capabilities in terms of deal flow.

Use case: working on an acquisition process for a CPG company

What we did:

  • Kick-off to define what the client is seeking, notably in terms of maturity.
  • Workshop with the client based on a mapping of the different innovation ecosystems adjacent to its activities to select some priorities and discuss inspiring examples of startup acquisition stories.
  • Identification of 20+ targets.
  • Workshop to select the most relevant to engage with.
  • DigitalFoodLab worked as a sparing partner during the acquisition process, notably to help design how the acquired startup could be integrated into the overall company’s strategy.

Results:

  • Different results from traditional M&A processes with a focus on the client’s innovation strategy.
  • Identification of a good match for an acquisition.

Use case: market due diligence on sugar alternatives

What we did:

  • Kick-off with the client to discuss its interest on this category, its expectations and existing level of information (notably on the target company).
  • Mapping of the ecosystem to analyse the different existing alternatives and technologies to compare them.
  • Interview (calls) with relevant startups made by our internal biotechnology expert.
  • Recommendation on whether to invest or not.

Results:

  • Clear view of the ecosystem and of the reasons to believe (or not) in each sub-category.
  • Enforceable recommendations based on facts and expertise.